About Pudee

Reliability, Responsibility and Rapidity

Founded in 2007, focus on the synthesis of small molecule compounds and the extraction of some natural compounds. We develop, produce and sell high-quality advanced intermediates and some APIs with competitive prices.
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Contact Info

  • Building 2, Handa Science and Technology Park
    No. 8 Pioneer Road
    High-tech Zone. Suzhou.
  • 86 512 6803 2792
    86 512 6803 2791
  • willdyhan@pudeepharm.com
    sales@pudeepharm.com

Product Details

Cobimetinib

Cobimetinib | 934660-93-2

Chemical Name: [3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl]methanone

CAS Number: 934660-93-2
Formula: C21H21F3IN3O2
Molecular weight: 531.31
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Product Description

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Cobimetinib (GDC-0973, XL-518, Cotellic) is a MEK inhibitor developed by Exelixis and Genentech. It was studied in combination with vemurafenib, a BRAF inhibitor, to treat several cancers.
In November 2015, the U.S. Food and Drug Administration approved cobimetinib for unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with vemurafenib

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